MIM1


CAS No. : 509102-00-5

(Synonyms: Inhibitor of Mcl-1)

509102-00-5
Price and Availability of CAS No. : 509102-00-5
Size Price Stock
5mg $90 In-stock
10mg $150 In-stock
25mg $300 In-stock
50mg $450 In-stock
100mg $680 In-stock
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Cat. No. : HY-16695
M.Wt: 347.43
Formula: C17H21N3O3S
Purity: >98 %
Solubility: DMSO : 50 mg/mL (ultrasonic)
Introduction of 509102-00-5 :

MIM-1 is an inhibitor of myeloid cell factor 1 (Mcl-1). IC50 & Target: Mcl-1[1] In Vitro: MIM-1 selectively targets the BH3 binding groove of Mcl-1, with Bak-dependent apoptotic activity. To estimate the sensitivity of HA and T98G cells to the apoptosis inhibitor MIM-1, the colorimetric MTT assay is used to detect cell viability and to determine the IC50 value. The IC50 value of the HA cell line is almost 5-fold lower (16.10 µM) compared with the IC50 of the T98G cell line (80.20 µM) after MIM-1 inhibitor treatment.

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