Catumaxomab
CAS No. : 509077-98-9
| Size | Price | Stock |
|---|---|---|
| 1mg | $400 | In-stock |
| 5mg | $1040 | In-stock |
| 10mg | $1665 | In-stock |
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| 100 mg | Get quote | |
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| Cat. No. : | HY-P9954 |
| M.Wt: | 1000.00 |
| Formula: | N/A |
| Purity: | >98 % |
| Solubility: | H2O |
Catumaxomab, a trifunctional IgG2 antibody, is composed of mouse and rat heavy and light chains and binds to human EpCAM and human CD 3 receptors. The Fc region of Catumaxomab region has binding affinity for FcγR1 (CD 64), FcγRIIA (CD 32a), and FcγRIII (CD 16). Catumaxomab can be used for anti-tumor research, especially epithelial cancers[1][2].
IC50 & Target:CD3E & EPCAM
In Vitro: Catumaxomab (0-5 ng/mL; 3-7 days) strongly inhibits the growth of FaDu tumor spheroids in coculture with PBMC with a dose-dependent manner[2].
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