1-Acetyl-β-carboline
CAS No. : 50892-83-6
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| Cat. No. : | HY-W060074 |
| M.Wt: | 210.23 |
| Formula: | C13H10N2O |
| Purity: | >98 % |
| Solubility: | DMSO : 50 mg/mL (ultrasonic) |
1-Acetyl-β-carboline is a metabolite of Streptomyces kasugaensis and antibacterial agent. 1-Acetyl-β-carboline increases tyrosinase activity, reduces ERK phosphorylation. 1-Acetyl-β-carboline exhibits antibacterial activity against methicillin-resistant Staphylococcus aureus (MRSA) strains with MICs ranging from 128 to 256 ug/mL. 1-Acetyl-β-carboline increases the melanin[1][2][3].
In Vitro:1-Acetyl-β-carboline (32-64 μg/mL) exhibits synergistic antimicrobial activity against MRSA strains when used in combination with β-lactam antibiotics[2].
1-Acetyl-β-carboline shows antibacterial activity against MRSA strains tested with MICs ranging from 128 to 256 ug/mL[2].
1-Acetyl-β-carboline (12.5-50 μM; 72 h) increases the melanin content and the tyrosinase activity in B16F10 melanoma cells[3].
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