Nervonic acid
CAS No. : 506-37-6
(Synonyms: Selacholeic acid; cis-15-Tetracosenoic acid)
| Size | Price | Stock |
|---|---|---|
| 250mg | $85 | In-stock |
| 1g | $175 | In-stock |
| 5g | $874 | In-stock |
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| Cat. No. : | HY-N2526 |
| M.Wt: | 366.62 |
| Formula: | C24H46O2 |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic) |
Nervonic acid is a monounsaturated fatty acid with oral activity. Nervonic acid exerts anti-inflammatory activity by inhibiting NF-κB signaling. Nervonic acid can be used in the study of neurodegenerative diseases[1][2][3].
In Vitro:Nervonic acid (0.01 μM, 48 h) can improve the activity of PC-12 cells and play a role as a neuroprotective mediator in the brain[1].
Nervonic acid (12.5, 25, 50 μM, 24 h) can decrease the inflammatory response of RAW264.7 cells induced by LPS and inhibit the activation of key signal pathways related to inflammation[3].
In Vivo:Nervonic acid (20, 40, 60 mg/kg, gavage for 7 days) protects the motor system against motor disorders in a PD mouse model[2].
Nervonic acid (5, 50, 100 mg/kg, dissolved in corn oil for 7 days) improves colonic inflammation by inhibiting the NF-κB signaling pathway in DSS-induced colitis mice[3].
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