Eggmanone
CAS No. : 505068-32-6
(Synonyms: EGM1)
| Size | Price | Stock |
|---|---|---|
| 1mg | $190 | Get quote |
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| 10 mg | Get quote | |
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| Cat. No. : | HY-121037 |
| M.Wt: | 416.58 |
| Formula: | C20H20N2O2S3 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Eggmanone (EGM1) is a potent and selective phosphodiesterase 4 (PDE4) antagonist with an IC50 of 72 nM for PDE4D3. Eggmanone shows approximately 40- to 50-fold selective for PDE4D3 over other PDEs. Eggmanone exerts its Hh-inhibitory effects through selective antagonism of PDE4, leading to protein kinase A activation and subsequent Hh blockade[1].
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