GW 441756
CAS No. : 504433-23-2
| Size | Price | Stock |
|---|---|---|
| 5mg | $65 | In-stock |
| 10mg | $100 | In-stock |
| 25mg | $190 | In-stock |
| 50mg | $290 | In-stock |
| 100mg | $435 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
| We match the lowest price on market. | ||
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| Cat. No. : | HY-18314 |
| M.Wt: | 275.30 |
| Formula: | C17H13N3O |
| Purity: | >98 % |
| Solubility: | DMSO : 17.5 mg/mL (ultrasonic;warming) |
GW 441756 is a potent and specific nerve growth factor (NGF) receptor tyrosine kinases A (TrkA) inhibitor (IC50=2 nM), which eliminates the BmK NSPK-induced neurite outgrowth[1][2][3].
IC50 & Target: IC50: 2 nM (TrkA)[3]
In Vitro: GW-441756 (1 µM; 48 hours; spinal cord neurons cells) abolishs BmK NSPK-induced neurite outgrowth[1].
GW-441756 (1 µM; 4 hours; PC12 cells) inhibits nerve growth factor induced neurite outgrowth[1].
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