Isoliquiritin
CAS No. : 5041-81-6
| Size | Price | Stock |
|---|---|---|
| 1mg | $50 | In-stock |
| 5mg | $90 | In-stock |
| 10mg | $153 | In-stock |
| 25mg | $305 | In-stock |
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| Cat. No. : | HY-N0765 |
| M.Wt: | 418.39 |
| Formula: | C21H22O9 |
| Purity: | >98 % |
| Solubility: | DMSO : 125 mg/mL (ultrasonic) |
Isoliquiritin, isolated from Licorice Root, inhibits angiogenesis and tube formation. Isoliquiritin also exhibits antidepressant-like, anti-oxidative, anti-Inflammatory effects and antifungal activity[1][2][3].
In Vitro: Isoliquiritin (0-400 μg/mL) inhibits the growth of a panel of plant pathogenic fungi[3].
Isoliquiritin (0-100 μg/mL, 4 h) inhibits sporangia germination of P. litchii[3].
Isoliquiritin (20 μM, 24 h) protects cell from Corticosterone (400 μM)-induced apoptosis in PC12 cells, and reduces LDH release, increases the activity of SOD, CAT, decreases the ROS and MDA level[4].
In Vivo: Isoliquiritin (0.31-3.1 mg/kg, i.p., once a day for 5 days) inhibits granuloma angiogenesis in mice[1].
Isoliquiritin (10-40 mg/kg, oral gavage) shows antidepressant-like effects in FST and TST tests in mice[2].
Isoliquiritin ((10 mg/kg/bw/day, p.o.) shows anti-oxidative and anti-Inflammatory properties, and relieves cationic BSA-Induced membranous glomerulonephritis in experimental rat model[5].
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