TX-1918
CAS No. : 503473-32-3
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| Cat. No. : | HY-112393 |
| M.Wt: | 228.24 |
| Formula: | C14H12O3 |
| Purity: | >98 % |
| Solubility: |
TX-1918 is an inhibitor for eukaryotic elongation factor 2 kinase (eEF2-K) and Src kinase with IC50 of 0.44 and 4.4 μM, respectively. TX-1918 exhibits cytotoxicity in cell HepG2 and HCT116, with IC50 of 2.07 and 230 μM, respectively. TX-1918 inhibits the C-terminal domain of HIV-1 CA (CA CTD)(IC50 =3.81 μM), and inhibits the viral replication (IC50 =15.16 μM)[1][2]. IC50 & Target:IC50: 44 μM (PKA), 44 μM (PKC), 4.4 μM (Src), 0.44 μM (eEF2 kinase)
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