Cucurbitacin IIb


CAS No. : 50298-90-3

50298-90-3
Price and Availability of CAS No. : 50298-90-3
Size Price Stock
5mg $210 In-stock
10mg $315 In-stock
25mg $560 In-stock
50mg $840 In-stock
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200 mg Get quote
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Cat. No. : HY-N1987
M.Wt: 520.70
Formula: C30H48O7
Purity: >98 %
Solubility: DMSO : 100 mg/mL (ultrasonic)
Introduction of 50298-90-3 :

Cucurbitacin IIb is an active component isolated from Hemsleya amabilis, induces apoptosis with anti-inflammatory activity. Cucurbitacin IIb inhibits phosphorylation of STAT3, JNK and Erk1/2, enhances the phosphorylation of IκB and NF-κB (p65), blocks nuclear translocation of NF-κB (p65) and decreases mRNA levels of IκBα and TNF-α[1].

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