Levalbuterol (hydrochloride)
CAS No. : 50293-90-8
(Synonyms: (R)-Albuterol (hydrochloride); (R)-Salbutamol (hydrochloride); Levosalbutamol (hydrochloride))
| Size | Price | Stock |
|---|---|---|
| 5mg | $57 | In-stock |
| 10mg | $85 | In-stock |
| 25mg | $130 | In-stock |
| 50mg | $170 | In-stock |
| 100mg | $230 | In-stock |
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| Cat. No. : | HY-B1675A |
| M.Wt: | 275.78 |
| Formula: | C13H22ClNO3 |
| Purity: | >98 % |
| Solubility: | H2O : 100 mg/mL (ultrasonic) |
Levalbuterol ((R)-Albuterol) hydrochloride is a short-acting β2-adrenergic receptor agonist and the active (R)-enantiomer of Salbutamol. Levalbuterol hydrochloride is a more potent bronchodilator than Salbutamol and has the potential for the treatment of COPD[1]. In Vitro: Levalbuterol (10 μM; 24 hours) hydrochloride induces 11β-HSD1 mRNA expression, however, it does not influence 11β-HSD2expression in airway epithelial cells[1]. Levalbuterol (10 μM; 24 hours) hydrochloride significantly reduces both LPS- and TNF-α-induced NF-κB activity while increasing GRE activation in an 11β-HSD1 dependent manner in a transformed mouse airway epithelial cell line[1]. In Vivo: Levalbuterol (subcutaneous injection; 1 mg/kg; 14 days) hydrochloride significantly decreases pulmonary inflammation in OVA mice, demonstrated a decrease in eosinophilia and IgE[2].
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