Rilonacept


CAS No. : 501081-76-1

(Synonyms: Arcalyst; IL 1 Trap; Interleukin 1 Trap)

501081-76-1
Price and Availability of CAS No. : 501081-76-1
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1mg $1080 In-stock
5mg $2850 In-stock
10mg $4560 In-stock
25mg $9120 In-stock
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Cat. No. : HY-108822
M.Wt: 1000.00
Formula: N/A
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 501081-76-1 :

Rilonacept (Arcalyst), a dimeric fusion protein, is a interleukin 1 inhibitor. Rilonacept consists of the ligand-binding domains of the extracellular portions of the IL-1R components linked to the Fc portion of human IgG1. Rilonacept can be used for the research of cryopyrin-associated periodic syndromes[1]. In Vitro: Rilonacept blocks IL-1α signaling by acting as a soluble decoy receptor that binds IL-1β and prevents its interaction with cell–surface receptors, thereby reducing the inflammatory process[1].

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