IK1 inhibitor PA-6


CAS No. : 500715-03-7

(Synonyms: PA-6)

500715-03-7
Price and Availability of CAS No. : 500715-03-7
Size Price Stock
5mg $69 In-stock
10mg $130 In-stock
25mg $250 In-stock
50mg $410 In-stock
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Cat. No. : HY-112544
M.Wt: 492.61
Formula: C31H32N4O2
Purity: >98 %
Solubility: DMSO : 125 mg/mL (ultrasonic)
Introduction of 500715-03-7 :

IK1 inhibitor PA-6 (PA-6), a pentamidine analogue, is a selective and potent IK1 (KIR2.x ion-channel-carried inward rectifier current) inhibitor, with IC50 values of 12-15 nM for human and mouse KIR2.x currents. IK1 inhibitor PA-6 (PA-6) elevates KIR2.1 protein expression and induces intracellular KIR2.1 accumulation. IK1 inhibitor PA-6 (PA-6) has the potential to treat atrial fibrillation and arrhythmia[1][2][3]. IC50 & Target: IC50: 12-15 nM (KIR2.x currents)[1].

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