MK-0873
CAS No. : 500355-52-2
| Size | Price | Stock |
|---|---|---|
| 1mg | $281 | In-stock |
| 5mg | $679 | In-stock |
| 10mg | $1018 | Get quote |
| 50 mg | Get quote | |
| 100 mg | Get quote | |
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| Cat. No. : | HY-108047 |
| M.Wt: | 422.44 |
| Formula: | C25H18N4O3 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
MK-0873 is a selective phosphodiesterase-4 (PDE4) inhibitor. MK-0873 increases intracellular levels of cyclic adenosine phosphate (cAMP) by inhibiting the activity of the PDE4 enzyme and subsequently activates protein kinase A (PKA). Activated PKA inhibits the activity of inflammatory cells and leads to direct relaxation of airway smooth muscle. MK-0873 can be used in studies of chronic obstructive pulmonary disease (COPD)[1].
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