Fluphenazine decanoate
CAS No. : 5002-47-1
| Size | Price | Stock |
|---|---|---|
| 5mg | $46 | In-stock |
| 10mg | $75 | In-stock |
| 25mg | $104 | In-stock |
| 50mg | $130 | In-stock |
| 100mg | $220 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-B1904 |
| M.Wt: | 591.77 |
| Formula: | C32H44F3N3O2S |
| Purity: | >98 % |
| Solubility: | DMSO : 125 mg/mL (ultrasonic);Ethanol : 50 mg/mL (ultrasonic) |
Fluphenazine decanoate is a CNS-penetrant dopamine D2 receptor inhibitor, is a long-acting phenothiazine neuroleptic. Fluphenazine can be used for schizophrenia research[1][2][3].
IC50 & Target:Dopamine D2 receptor[2]
In Vitro:Fluphenazine decanoate shows activity against T. gondii in human fibroblast cell cultures with an IC50 value of 1.7 mM[1].
In Vivo:Fluphenazine decanoate (0.22 mg/kg and followed by 0.33 mg/kg; i.m.; 8 times every 3 weeks), as an antipsychotic, increases sensitivity to dopamine on monkey model following extended treatment[2].
Fluphenazine decanoate (25 mg/kg; i.m.; 6 times every 3 weeks; 24 weeks) induces mouth movements in the rat, serves as a pharmacological model of human tardive dyskinesia[3].
Fluphenazine decanoate (1, 2, 3 mg/kg/d; s.c.; 60 d) shows antifertility effects and induces hyperprolactinemia concomitant with gonadotropin suppression in adult male rat[4].
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