Olivetol


CAS No. : 500-66-3

500-66-3
Price and Availability of CAS No. : 500-66-3
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Cat. No. : HY-W008364
M.Wt: 180.25
Formula: C11H16O2
Purity: >98 %
Solubility: DMSO : 100 mg/mL (ultrasonic)
Introduction of 500-66-3 :

Olivetol is a naturally phenol found in lichens and produced by certain insects, acting as a competitive inhibitor of the cannabinoid receptors CB1 and CB2[3]. Olivetol also inhibits CYP2C19 and CYP2D6 activity, with IC50s of 15.3 μM, 7.21 μM and Kis of 2.71 μM, 2.87 μM, respectively[1][2]. IC50 & Target:IC50: 7.21 μM (CYP2D6)[2], 15.3 μM (CYP2C19)[1]
Ki: 2.71 μM (CYP2C19)[1], 2.87 μM (CYP2D6)[2]
CB1, CB2[3]
In Vitro: Olivetol inhibits the (S)-mephenytoin 4'-hydroxylase activity of CYP2C19 activity with an IC50 of 15.3 μM and a Ki of 2.71 μM[1]. Olivetol also inhibits AMMC O-demethylase activity of recombinant CYP2D6 with an IC50 of 7.21 μM and a Ki of 2.87 μM[2].
Olivetol is a competitive inhibitor of the cannabinoid receptors CB1 and CB2[3].

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