Actinomycin D (Standard)
CAS No. : 50-76-0
(Synonyms: Dactinomycin (Standard); Actinomycin IV (Standard))
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| Cat. No. : | HY-17559R |
| M.Wt: | 1255.42 |
| Formula: | C62H86N12O16 |
| Purity: | >98 % |
| Solubility: |
Actinomycin D (Standard) (Dactinomycin (Standard)) is the analytical standard of Actinomycin D (HY-17559). This product is intended for research and analytical applications. Actinomycin D (Dactinomycin) is an antibiotic found in Streptomyces microsporum with antibacterial and anti-tumor effects. Actinomycin D is an inhibitor of RNA and protein synthesis. Actinomycin D can inhibit the protein synthesis of bacteria, directly bind to the guanine groups of single-stranded or double-stranded DNA in the transcriptional initiation complex, inhibit the activity of DNA-dependent RNA polymerase, and interfere with the transcription process of DNA, thereby inhibiting mRNA synthesis. Actinomycin D inhibits DNA repair with an IC50 value of 0.42 μM. Actinomycin D is also an autophagy activator. Actinomycin D is promising for research of cancer and cardiovascular diseases.
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