Phentolamine


CAS No. : 50-60-2

50-60-2
Price and Availability of CAS No. : 50-60-2
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5mg $50 In-stock
10mg $80 In-stock
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Cat. No. : HY-12717
M.Wt: 281.35
Formula: C17H19N3O
Purity: >98 %
Solubility: DMSO : 125 mg/mL (ultrasonic)
Introduction of 50-60-2 :

Phentolamine is a potent, selective and orally active α1 adrenergic and α2 adrenergic receptor antagonist. Phentolamine can be used for the treatment of erectile dysfunction[1][2][3]. In Vivo: Phentolamine (5-20 mg/kg; i.p.) effectively inhibits the seizures elicited by strychnine (2 mg/kg, i.p.) and attenuates the seizure-potentiating effect of DOPS (4 mg/kg, i.p.) in mouse[2].
Phentolamine (1 mg/kg; i.p.) increases insulin secretion by inhibition of b-cell a2A-adrenoceptors in mouse[3].

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