Estradiol benzoate
CAS No. : 50-50-0
(Synonyms: β-Estradiol 3-benzoate; 17β-Estradiol 3-benzoate)
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| 1g | $66 | In-stock |
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| Cat. No. : | HY-B1192 |
| M.Wt: | 376.49 |
| Formula: | C25H28O3 |
| Purity: | >98 % |
| Solubility: | DMSO : 50 mg/mL (ultrasonic;warming;heat to 60°C);H2O : 0.1 mg/mL (ultrasonic) |
Estradiol benzoate (β-Estradiol 3-benzoate) is a HBx protein inhibitor and inhibits androgen and hepatitis B virus (HBV) transcription, replication. Estradiol benzoate shows antifertility effects, anti- Toxoplasma gondii activity and can improve memory behavior of Ovariectomy (Ovx) female mice[1][2][3][4][5].
In Vitro:Estradiol benzoate (5-75 μM, 24 h-48 h) has a downregulation effect on HBV translation, transcription, and replication in SBHX21 cells[3].
Estradiol benzoate (0-500 μM, 72 h) has toxicity to Human foreskin fibroblasts (HFFs)[4].
In Vivo:Estradiol benzoate (20-100 μg/kg, Subcutaneous injection, once a day for 4-5 weeks) improves learning and memory behavior of Ovx female mice[1].
Estradiol benzoate (0.015-15000 μg/kg, Subcutaneous injection, single dose) advances male puberty in male Sprague-Dawley (SD) rats[2].
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