Clomiphene (citrate)
CAS No. : 50-41-9
(Synonyms: Clomifene citrate)
| Size | Price | Stock |
|---|---|---|
| 500mg | $55 | In-stock |
| 1g | $66 | In-stock |
| 5g | $119 | In-stock |
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| Cat. No. : | HY-B0463 |
| M.Wt: | 598.08 |
| Formula: | C32H36ClNO8 |
| Purity: | >98 % |
| Solubility: | H2O : 1 mg/mL (ultrasonic);DMSO : ≥ 50 mg/mL |
Clomiphene citrate (Clomifene citrate) is an orally active estrogen-receptor modulator. Clomiphene citrate has anti-cancer actixity, induces perturbations during meiotic maturation and cytogenetic abnormalities and ameliorates in managing psychiatric and cognitive impairment[1][2][3].
In Vitro:Clomiphene citrate (50 μM, 1-30 min) inhibits the viability of PC3 human prostate cancer cells[1].
Clomiphene citrate (1-5 μg/mL, 18 h) induces chromosome abnormalities in mouse oocytes[2].
In Vivo:Clomiphene citrate (25-100 mg/kg, Intraperitoneal injection, single dose) induces chromosome abnormalities in mouse metaphase II oocytes[2].
Clomiphene citrate (1 mg/kg, Oral, once a day for 15 days) with carvedilol (HY-B0006) has anxiolytic potential and improved cognitive functions in letrozole(HY-14248)-induced polycystic ovary syndrome (PCOS) rats[3].
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