Propantheline (bromide)
CAS No. : 50-34-0
| Size | Price | Stock |
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| Cat. No. : | HY-B1188 |
| M.Wt: | 448.39 |
| Formula: | C23H30BrNO3 |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 100 mg/mL;H2O : 50 mg/mL (ultrasonic) |
Propantheline bromide is an orally active mAChR antagonist. Propantheline bromide can be used in the research of smooth muscle dysfunction, excessive sweating, cramps or spasms of the stomach, intestines or bladder, and involuntary urination[1][2][3].
IC50 & Target: mAChR[1]
In Vitro: Propantheline bromide (10 μM-1 mM) decreases urinary bladder smooth muscle reactivity to Acetylcholine[1].
In Vivo: Propantheline bromide (oral administration, 10-300 mg/kg) decreased the fecal pellet count and the incidences diarrhea in restraint stress-induced bowel dysfunction rats[3].
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