Estradiol


CAS No. : 50-28-2

(Synonyms: β-Estradiol; E2; 17β-Estradiol; 17β-Oestradiol)

50-28-2
Price and Availability of CAS No. : 50-28-2
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500mg $20 In-stock
1g $23 In-stock
5g $35 In-stock
10g $43 In-stock
25g $105 In-stock
100g $325 In-stock
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Cat. No. : HY-B0141
M.Wt: 272.39
Formula: C18H24O2
Purity: >98 %
Solubility: Ethanol : 20 mg/mL (ultrasonic);DMSO : 100 mg/mL (ultrasonic)
Introduction of 50-28-2 :

Estradiol (β-Estradiol) is a steroid hormone and the major female sex hormone. Estradiol can up-regulate the expression of neural markers of human endometrial stem cells (hEnSCs) and promote their neural differentiation. Estradiol can be used for the research of cancers, neurodegenerative diseases and neural tissue engineering[1][2]. In Vitro: Estradiol (10 nM, 7 days) induces neural differentiation and increased neurite branching of human endometrial stem cells (hEnSCs)[1].
Estradiol (17β-estradiol, 10 nM, 7 days) increases the expression of neuron-like cell markers (Tuj-1, nestin and NF-H) in neural-like cells differentiated from hEnSCs[1].
In Vivo: Estradiol (1 nM, the hippocampal slices from FBN-ARO-KO mice) rescues long-term potentiation (LTP) amplitude[1].
Estradiol (0.0167 mg, implanted s.c., FBN-ARO-KO mice) rescues the molecular and functional deficits in FBN-ARO-KO mice[1].

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