Tobramycin (sulfate)
CAS No. : 49842-07-1
(Synonyms: Nebramycin Factor 6 (sulfate); Deoxykanamycin B (sulfate))
| Size | Price | Stock |
|---|---|---|
| 100mg | $60 | In-stock |
| 500mg | $120 | In-stock |
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| Cat. No. : | HY-B0441A |
| M.Wt: | 712.18 |
| Formula: | C18H37N5O9.5/2H2O4S |
| Purity: | >98 % |
| Solubility: | DMSO : < 1 mg/mL (ultrasonic;warming;heat to 60°C);H2O : 250 mg/mL (ultrasonic) |
Tobramycin (Nebramycin Factor 6) sulfate is a parenterally administered, broad spectrum aminoglycoside antibiotic that is widely used in the treatment of moderate to severe bacterial infections due to sensitive organisms. Tobramycin sulfate can be used to pneumonia research caused by Pseudomonas aeruginosa[1][2][3][4].
In Vitro:Tobramycin (0-50 ng/mL; 24 hours) sulfate combinates with mycobacterium fortuitum enzyme (PodA) can greatly decreases P. aeruginosa cell viability[2].
In Vivo:Tobramycin (50-400 mg/kg/day, i.p., once every 4h) sulfate combinates with Meropenem (HY-13678) produces bacterial cell kill effect at low doses of both drugs in murine pneumonia model. [3].
Tobramycin (s.c., single dose) sulfate LD50 values in mice and rats are 441 and 969 mg/kg, respectively[4].
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