Guvacine
CAS No. : 498-96-4
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| Cat. No. : | HY-N2482 |
| M.Wt: | 127.14 |
| Formula: | C6H9NO2 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Guvacine, an alkaloid found in the nut of Areca catechu, is a potent GABA uptakp inhibitor. Guvacine inhibits rat GAT-1, rat GAT-2 and rat GAT-3 with IC50 values of 39 μM, 58 μM and 378 μM, respectively[1]. IC50 & Target: IC50: 39 μM (rat GAT-1), 58 μM (rat GAT-2), 378 μM (rat GAT-3), 14 μM (human GAT-1), 119 μM (huam GAT-3) and 1870 μM (human BGT-3)[1]
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