CAS No. : 498-95-3
(Synonyms: (±)-β-Homoproline; Hexahydronicotinic acid; 3-Carboxypiperidine)
| Size | Price | Stock |
|---|---|---|
| 25g | $10 | In-stock |
| 100g | $39 | In-stock |
| 500g | $164 | In-stock |
| 1000g | $326 | In-stock |
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| Cat. No. : | HY-69359 |
| M.Wt: | 129.16 |
| Formula: | C6H11NO2 |
| Purity: | >98 % |
| Solubility: | DMSO : < 1 mg/mL (ultrasonic);H2O : 50 mg/mL (ultrasonic) |
Nipecotic acid ((±)-β-Homoproline) is a potent inhibitor of neuronal and glial-aminobutyric acid (GABA) uptake in vitro. Nipecotic acid can also directly activate GABAA-like chloride channels, with an EC50 of approximately 300?μM[1][2]. IC50 & Target: GABA Receptor[1] In Vitro: Nipecotic acid (1?mM) activated inward unitary currents when applied to outside-out patches of paraventricular neurones[1]. In Vivo: Nipecotic acid does not readily cross the blood-brain barrier (BBB)[2].
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