Forigerimod


CAS No. : 497156-60-2

(Synonyms: IPP-201101)

497156-60-2
Price and Availability of CAS No. : 497156-60-2
Size Price Stock
1mg $80 In-stock
5mg $200 In-stock
10mg $330 In-stock
25mg $620 In-stock
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Cat. No. : HY-105037
M.Wt: 2638.94
Formula: C117H181N34O32PS
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 497156-60-2 :

Forigerimod (IPP-201101) is a CD4 T-cell modulator. Forigerimod is a 21-amino-acid fragment of U1 small nuclear ribonucleoprotein 70 kDa that is phosphorylated at Ser140. Forigerimod can potently inhibit autophagy. Forigerimod can be used for the research of autoimmune disorders, such as systemic lupus erythematosus (SLE) [1][2][3][4]. In Vivo: Forigerimod (P140) (i.v.; 100 μg in 100 μL saline per mouse) directly acts on chaperone-mediated autophagy, rescues MRL/lpr mice from cellular infiltration and autophagy defects occurring in salivary glands[4].

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