AR-C155858
CAS No. : 496791-37-8
| Size | Price | Stock |
|---|---|---|
| 1mg | $132 | In-stock |
| 5mg | $372 | In-stock |
| 10mg | $624 | In-stock |
| 25mg | $1124 | In-stock |
| 50mg | $1600 | In-stock |
| 100mg | $2240 | In-stock |
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| Cat. No. : | HY-13248 |
| M.Wt: | 461.53 |
| Formula: | C21H27N5O5S |
| Purity: | >98 % |
| Solubility: | DMSO : 70 mg/mL (ultrasonic) |
AR-C155858 is a selective monocarboxylate transporter MCT1 and MCT2 inhibitor with Kis of 2.3 nM and 10 nM, respectively. IC50 & Target: Ki: 2.3 nM (MCT1), 10 nM (MCT2) In Vitro: AR-C155858 (10 nM-100 nM) inhibits MCT1/MCT2 C-terminal chimaeras[1]. AR-C155858 inhibits MCT2, and the 70% inhibition seen at 10 nM is followed by a gradually increasing inhibition which can only be explained by a Ki value of significantly less than 10 nM. AR-C155858 inhibits MCT1 expressed in Xenopus oocytes in a time- and concentration-dependent manner[2].
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