Coumaran
CAS No. : 496-16-2
(Synonyms: 2,3-Dihydrobenzofuran)
| Size | Price | Stock |
|---|---|---|
| 5g | $5 | In-stock |
| 10g | $9 | In-stock |
| 25g | $18 | In-stock |
| 100g | $45 | In-stock |
| 500g | $195 | In-stock |
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| 2 kg | Get quote | |
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| Cat. No. : | HY-75247 |
| M.Wt: | 120.15 |
| Formula: | C8H8O |
| Purity: | >98 % |
| Solubility: | H2O : 150 mg/mL (ultrasonic);DMSO : 150 mg/mL (ultrasonic) |
Coumaran (2,3-Dihydrobenzofuran) is an AChE inhibitor with antileishmanial activity. Coumaran may acquire antiparasitic capabilities through activation of macrophages and exert immunomodulatory activity. Coumaran can be used as a biopesticide.[2].
IC50 & Target:AChE[1]
In Vitro: Coumaran is active against promastigote (IC50=1.042 μM) and amastigote (IC50=1.43 μM) forms, demonstrating potent antileishmanial activity [2].
Coumaran (0.5-13 μM; 48 h) Not significantly cytotoxic to macrophages or erythrocytes [2].
Coumaran (0.5-13 μM; 24 h) increases phagocyte and lysosomal activity and nitrite (NO2- ) level [2].
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