Tigloidin


CAS No. : 495-83-0

(Synonyms: Tigloyl pseudotropine; Tiglylpseudotropine; Tiglyssin)

495-83-0
Price and Availability of CAS No. : 495-83-0
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5mg $200 In-stock
10mg $350 In-stock
25mg $700 In-stock
50mg $1200 In-stock
100mg $1650 In-stock
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Cat. No. : HY-U00082
M.Wt: 223.31
Formula: C13H21NO2
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 495-83-0 :

Tigloidin is an analogue of atropine, with anticholinergic activity. In Vivo: Tigloidine hydrobromide (20-60 mg/kg, i.p.) fails to protect the mice against the lethal effect of physostigmine, but at 100 mg/kg and above, it protects 80% of the animals against the lethal effect. Tigloidine markedly prevents tremor and salivation produced by tremorine at 80-100 mg/kg, but fails to prevent these effects in doses up to 40 mg/kg. Tigloidine (up to 100 mg/kg, i.p) does not significantly affects reserpine and tetrabenazine induced sedation and ptosis in mice. Tigloidine (25-50 mg/kg, i.p.) also fails to cause any behavioral changes in the cats[1].

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