Dehydroemetine
CAS No. : 4914-30-1
| Size | Price | Stock |
|---|---|---|
| 5mg | $430 | In-stock |
| 10mg | $650 | In-stock |
| 25mg | $1300 | In-stock |
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| 100 mg | Get quote | |
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| Cat. No. : | HY-121241 |
| M.Wt: | 478.62 |
| Formula: | C29H38N2O4 |
| Purity: | >98 % |
| Solubility: | DMSO : 50 mg/mL (ultrasonic) |
Dehydroemetine is an orally active antiparasitic agent. Dehydroemetine can inhibit parasites such as Entamoeba histolytica, and it can also be used in the research of parasitic diseases like visceral leishmaniasis[1][2][3].
In Vitro: Dehydroemetine (10 mg/L) can inhibit the growth of Entamoeba histolytica in the culture medium[1].
Dehydroemetine (2-100 μg/mL) does not show spasmogenic effects in the isolated guinea pig ileum, but it can reversibly antagonize the ileal contractions induced by acetylcholine, Histamine (HY-B1204), and nicotine[2].
In Vivo: Dehydroemetine (10 mg/kg; intravenous injection; single dose) is mainly distributed in the liver and spleen in mice, with a relatively low concentration in the heart[3].
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