2,4,5-Trimethoxybenzoic acid
CAS No. : 490-64-2
(Synonyms: Asaronic acid)
| Size | Price | Stock |
|---|---|---|
| 10g | $10 | In-stock |
| 25g | $16 | In-stock |
| 100g | $53 | In-stock |
| 500g | $170 | In-stock |
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| Cat. No. : | HY-Y0586 |
| M.Wt: | 212.20 |
| Formula: | C10H12O5 |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic) |
2,4,5-Trimethoxybenzoic acid (Asaronic acid) is a compound identified in purple perilla extracts. 2,4,5-Trimethoxybenzoic acid inhibits LPS (HY-D1056)-induced inflammatory responses, inhibits the activation of NF-κB and STAT signaling pathways. 2,4,5-Trimethoxybenzoic acid inhibits M1 macrophage phenotype-mediated inflammation in diabetes[1].
In Vitro:2,4,5-Trimethoxybenzoic acid (0-20 μg/mL, 24-72 h) inhibits the secretion of IL-6 and MCP-1, reduces the expression of TLR4, CD36, and CD68 in LPS (HY-D1056)-induced J774A.1 macrophage[1].
2,4,5-Trimethoxybenzoic acid (0-20 μg/mL, 48 h) inhibits glucose-induced expression of HIF-1α, VEGF, TLR4, iNOS and IL-6, promotes the expression of Arg-1 and IL-10 in glucose-stimulated J774A.1 macrophages[1].
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