Br-C3-methyl ester


CAS No. : 4897-84-1

4897-84-1
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Cat. No. : HY-W004701
M.Wt: 181.03
Formula: C5H9BrO2
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 4897-84-1 :

Br-C3-methyl ester is a Alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTAC PD-1/PD-L1 degrader-1 (HY-131183)[1]. In Vitro: PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

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