Curcumol
CAS No. : 4871-97-0
(Synonyms: (-)-Curcumol)
| Size | Price | Stock |
|---|---|---|
| 5mg | $55 | In-stock |
| 10mg | $77 | In-stock |
| 25mg | $135 | In-stock |
| 50mg | $185 | In-stock |
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| 200 mg | Get quote | |
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| Cat. No. : | HY-N0104 |
| M.Wt: | 236.35 |
| Formula: | C15H24O2 |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 100 mg/mL |
Curcumol ((-)-Curcumol), a bioactive sesquiterpenoid, possesses numerous pharmacological activities like anticancer, antimicrobial, antifungal, antiviral, and antiinflammatory. Curcumol is a potent inducer of apoptosis in numerous cancer cells via targeting key signaling pathways as MAPK/ERK, PI3K/Akt and NF-κB which are generally deregulated in several cancers[1].
In Vitro: Curcumol ((-)-Curcumol) is the major component extracted from root of Rhizoma Curcumae. Curcumol exerts anticancer effect in cholangiocarcinoma cells via down-regulating CDKL3[2]
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Curcumol induces cell cycle arrest in colon cancer cells via reactive oxygen species and Akt/ GSK3β/cyclin D1 pathway[3]
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Curcumol suppresses breast cancer cell metastasis by inhibiting MMP-9 via JNK1/2 and Akt-dependent NF-κB signaling pathways[4].
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