Elemicin
CAS No. : 487-11-6
| Size | Price | Stock |
|---|---|---|
| 5g | $123 | In-stock |
| 25g | $514 | In-stock |
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| Cat. No. : | HY-N6807 |
| M.Wt: | 208.25 |
| Formula: | C12H16O3 |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic) |
Elemicin is an orally active alkenylbenzene widely distributed in many herbs and spices. Elemicin inhibits Stearoyl-CoA Desaturase 1 (SCD1) by metabolic activation. Elemicin has anti-influenza activities, antimicrobial, antioxidant, and antiviral activities. Elemicin and its reactive metabolite of 1′-Hydroxyelemicin can induce hepatotoxicity[1][2][3][4]. IC50 & Target:SCD1[1] In Vitro:Elemicin (62.5, 125, 250, 500, 1000 μM) has an IC50 value of 910 μM in HepG2 cells[2]. In Vivo:Elemicin (500 mg/kg; orally gavage; every 24 h for 3 weeks) impairs liver function in mice. Elemicin inhibits liver SCD1, leading to a disequilibrium of lysophosphatidylcholines (LPCs)[3].
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