Bicuculline (Standard)
CAS No. : 485-49-4
(Synonyms: (+)-Bicuculline (Standard))
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| Cat. No. : | HY-N0219R |
| M.Wt: | 367.35 |
| Formula: | C20H17NO6 |
| Purity: | >98 % |
| Solubility: | DMSO : 50 mg/mL (ultrasonic);H2O : < 0.1 mg/mL |
Bicuculline (Standard) is the analytical standard of Bicuculline. This product is intended for research and analytical applications. Bicuculline ((+)-Bicuculline) is A competing neurotransmitter GABAA receptor antagonist (IC50=2 μM). Bicuculline also blocks Ca2+ activating potassium (SK) channels and subsequently blocks slow post-hyperpolarization (slow AHP). Bicuculline has anticonvulsant activity. Bicuculline can be used to induce seizures in mice[1][2][3][4]. IC50 & Target:IC50: 2 μM (GABAA)[3]
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