N-Nornuciferine
CAS No. : 4846-19-9
Price and Availability of
CAS No. : 4846-19-9
| Size | Price | Stock |
|---|---|---|
| 5mg | $210 | In-stock |
| 10mg | $360 | In-stock |
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| 100 mg | Get quote | |
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| Cat. No. : | HY-N2129 |
| M.Wt: | 281.35 |
| Formula: | C18H19NO2 |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic) |
Introduction of
4846-19-9
:
N-Nornuciferine is an aporphine alkaloid in lotus leaf that significantly inhibits CYP2D6 with IC50 and Ki of 3.76 and 2.34 μM, respectively. IC50 & Target:IC50: 3.76 μM (CYP2D6)[1]
Ki: 2.34 μM (CYP2D6)[1]
In Vitro: The herb of lotus leaves is a commonly used traditional Chinese medicine with a wide range of pharmacological and physiological activities, particularly the reduction of the blood triglyceride and cholesterol levels. N-Nornuciferine strongly inhibits CYP2D6 activity but shows weak or no inhibition of the other four P450 isoenzymes (CYP2C19, CYP3A4, CYP2E1, CYP2C9). N-Nornuciferine competitively inhibits the CYP2D6-catalyzed dextromethorphan o-demethylation with apparent Ki values of 2.34 μM[1].Lorem ipsum dolor sit amet, consectetur adipisicing elit. Autem earum hic iste maiores, nam neque rem suscipit. Adipisci consequatur error exercitationem fugit ipsam optio qui, quibusdam repellendus sed vero! Debitis.
Inquiry Information- Product Name:
- N-Nornuciferine
- Cat. No.:
- HY-N2129
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