ProTx-I
CAS No. : 484598-35-8
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| Cat. No. : | HY-P1073 |
| M.Wt: | 3987.49 |
| Formula: | C171H245N53O47S6 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
ProTx-I, a venom toxin of the tarantula Thrixopelma pruriens, is a potent, selective CaV3.1 channel blocker with IC50 values of 0.2 μM and 31.8 μM for hCaV3.1 and hCaV3.2 respectively. ProTx-I is also a potent blocker for voltage-gated Na+ channels and inhibits KV 2.1 channels[1][2].
IC50 & Target:IC50: 0.2 μM (hCaV3.1) and 31.8 μM (hCaV3.2)[1]
Na+ channels[2]
KV 2.1 channels[2]
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