9-Phenanthrol


CAS No. : 484-17-3

(Synonyms: 9-Hydroxyphenanthrene; NSC 50554)

484-17-3
Price and Availability of CAS No. : 484-17-3
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Cat. No. : HY-108457
M.Wt: 194.23
Formula: C14H10O
Purity: >98 %
Solubility: DMSO : 100 mg/mL (ultrasonic)
Introduction of 484-17-3 :

9-Phenanthrol (9-Hydroxyphenanthrene) is a selective TRPM4 inhibitor with an IC50 of 17 μM. 9-Phenanthrol has no inhibitory activity on TRPM5, TRPC6, and CFTR. 9-Phenanthrol can be used for the research of ischemia-reperfusion injury[1][2]. In Vitro:9-Phenanthrol (20 µM) can reduce myocardial dysfunction in isolated rat hearts subjected to ischemia and reperfusion, as shown by significant improvement in function and reduction in infarct size[1].

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