Toddalolactone
CAS No. : 483-90-9
| Size | Price | Stock |
|---|---|---|
| 1mg | $50 | In-stock |
| 5mg | $100 | In-stock |
| 10mg | $150 | In-stock |
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| Cat. No. : | HY-N0518 |
| M.Wt: | 308.33 |
| Formula: | C16H20O6 |
| Purity: | >98 % |
| Solubility: | DMSO : 50 mg/mL (ultrasonic);H2O : < 0.1 mg/mL (ultrasonic) |
Toddalolactone, a main component of Toddalia asiatica, inhibits the activity of recombinant human plasminogen activator inhibitor-1 (PAI-1), with an IC50 value of 37.31 μM[1]. In Vitro: Toddalolactone, a natural coumarin, inhibits PAI-1 activity by preventing the formation of a stable PAI-1/uPA covalent complex, suggesting that the inhibitory effect of Toddalolactone may be due to the interference of close contact between plasminogen activator and the active center of PAI-1[1].
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