MC-DOXHZN (hydrochloride)
CAS No. : 480998-12-7
(Synonyms: (E/Z)-Aldoxorubicin (hydrochloride); Doxorubicin(6-maleimidocaproyl)hydrazone (hydrochloride))
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| 5mg | $160 | In-stock |
| 10mg | $280 | In-stock |
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| Cat. No. : | HY-16261B |
| M.Wt: | 787.21 |
| Formula: | C37H43ClN4O13 |
| Purity: | >98 % |
| Solubility: | H2O : 12.5 mg/mL (ultrasonic;warming;heat to 60°C);DMSO : 25 mg/mL (ultrasonic) |
MC-DOXHZN ((E/Z)-Aldoxorubicin) hydrochloride is an albumin-binding proagent of Doxorubicin (DNA topoisomerase II inhibitor), with acid-sensitive properties[1]. In Vitro:MC-DOXHZ hydrochloride is the key component used to conjugate doxorubicin (DOX, HY-15142A) with the anti-Midkine (MK) monoclonal antibody to form mAb-DOX. mAb-DOX (100 μg/mL, 96 hours) can inhibit 73% of HepG2 cell growth[2].
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