MC-DOXHZN (hydrochloride)
CAS No. : 480998-12-7
(Synonyms: (E/Z)-Aldoxorubicin (hydrochloride); Doxorubicin(6-maleimidocaproyl)hydrazone (hydrochloride))
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| 10mg | $280 | In-stock |
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| Cat. No. : | HY-16261B |
| M.Wt: | 787.21 |
| Formula: | C37H43ClN4O13 |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic) |
MC-DOXHZN ((E/Z)-Aldoxorubicin; Doxorubicin(6-maleimidocaproyl)hydrazone) hydrochloride is an albumin-binding proagent of Doxorubicin (HY-15142A) (DNA topoisomerase II inhibitor), with acid-sensitive properties. MC-DOXHZN hydrochloride can be used to synthesize ADC[1]. In Vitro:MC-DOXHZN hydrochloride conjugates to DTT-thiolated monoclonal antibodies (chimeric BR96, BR64, L6, human IgG) to form stable thioether-linked immunoconjugates[1].
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