| Size | Price | Stock |
|---|---|---|
| 1mg | $45 | In-stock |
| 5mg | $110 | In-stock |
| 10mg | $180 | In-stock |
| 25mg | $370 | In-stock |
| 50 mg | Get quote | |
| 100 mg | Get quote | |
| We match the lowest price on market. | ||
We offer a substantial discount on larger orders, please inquire via [email protected]
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| Cat. No. : | HY-N2897 |
| M.Wt: | 288.25 |
| Formula: | C15H12O6 |
| Purity: | >98 % |
| Solubility: | DMSO : 250 mg/mL (ultrasonic);H2O : < 0.1 mg/mL |
Dihydrokaempferol is isolated from Bauhinia championii (Benth). Dihydrokaempferol induces apoptosis and inhibits Bcl-2 and Bcl-xL expression. Dihydrokaempferol is a good candidate for new antiarthritic drugs[1]. IC50 & Target:Apoptosis; Bcl-2; Bcl-xL[1] In Vitro: Dihydrokaempferol (0.3-300 μM; 48 hours) has no significant effect on normal synoviocytes, but dependently decreases the viability of RA-FLSs[1]. Dihydrokaempferol (3-30 μM; 48 hours) increases the percentage of apoptotic cells (including early and late apoptotic cells; ~3.8% and ~9.6%, respectively)[1]. Dihydrokaempferol (3-30 μM; 48 hours) promotes Bax and Bad expression and inhibits Bcl-2 and Bcl-xL expression, increases the cleaved fragments of caspase-3, caspase-9 and cleaved PARP[1].
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