Oroxylin A
CAS No. : 480-11-5
(Synonyms: Baicalein 6-methyl ether; 6-Methoxybaicalein)
| Size | Price | Stock |
|---|---|---|
| 250mg | $60 | In-stock |
| 1g | $160 | In-stock |
| 5g | $480 | In-stock |
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| Cat. No. : | HY-N0560 |
| M.Wt: | 284.26 |
| Formula: | C16H12O5 |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 32 mg/mL |
Oroxylin A is an active flavonoid compound with strong anti-cancer effects. Oroxylin A inhibits the IL-6/STAT3 pathway and NF-κB signaling, inhibits cell proliferation and induces apoptosis. Oroxylin A inhibits colitis-related carcinogenesis[1][2][3][4][5].
In Vitro: Oroxylin A (20 μM; 24 h) inhibits the growth, proliferation, and migration of MDA-MB-231 cells. Oroxylin A also inhibits the invasion of MDA-MB-231 and inhibits its epithelial-to-mesenchymal transition (EMT) process[4].
Oroxylin A (20 μM; 24 h) also inhibits the expression of pro-inflammatory cytokines and inhibits the NF-κB signaling pathway[4].
The anti-inflammatory effect of Oroxylin A is abolished by TNF-α[4].
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