AUDA
CAS No. : 479413-70-2
| Size | Price | Stock |
|---|---|---|
| 5mg | $35 | In-stock |
| 10mg | $55 | In-stock |
| 50mg | $160 | In-stock |
| 100mg | $256 | In-stock |
| 250mg | $461 | In-stock |
| 500 mg | Get quote | |
| 1 g | Get quote | |
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| Cat. No. : | HY-108570 |
| M.Wt: | 392.58 |
| Formula: | C23H40N2O3 |
| Purity: | >98 % |
| Solubility: | DMSO : 125 mg/mL (ultrasonic) |
AUDA (compound 43) is a potent soluble epoxide hydrolase (sEH) inhibitor with IC50s of 18 and 69 nM for the mouse and human sEH, respectively[1]. AUDA has anti-inflammatory activity[2].
IC50 & Target: IC50: 18 nM (mouse sEH) and 69 nM (human sEH)[1]
In Vitro: AUDA (0.3-10 μg/mL; 48 hours) dose-dependently suppresses the proliferation of rat VSMCs exposed to PDGF[2].
AUDA (0.3-10 μg/mL; 30 min) dose-dependently upregulats COX-2 expression[2].
AUDA (10, 50 and 100 μM) augments the migratory ability of HCAECs in a dose-dependent manner[3].
AUDA significantly increases the adhesion ability of HCAECs[3].
In Vivo: AUDA (i.p.; 10 mg/kg; 14 days) reduces TNF-α, MMP-9 and IL-1β expression levels[3].
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