CUDA
CAS No. : 479413-68-8
| Size | Price | Stock |
|---|---|---|
| 5mg | $50 | In-stock |
| 10mg | $80 | In-stock |
| 25mg | $160 | In-stock |
| 50mg | $260 | In-stock |
| 100mg | $420 | In-stock |
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| 500 mg | Get quote | |
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| Cat. No. : | HY-121538 |
| M.Wt: | 340.50 |
| Formula: | C19H36N2O3 |
| Purity: | >98 % |
| Solubility: | DMSO : 25 mg/mL (ultrasonic) |
CUDA is a potent inhibitor of soluble epoxide hydrolase (sEH), with IC50s of 11.1 nM and 112 nM for mouse sEH and human sEH, respectively[1]. CUDA selectively increases peroxisome proliferator-activated receptor (PPAR) alpha activity. CUDA may be valuable for the research of cardiovascular disease[2].
In Vitro:CUDA (10 μM; 18 hours) produces 6- and 3-fold increases of PPARalpha in COS-7 cells[2].
CUDA does not alter PPARα protein expression, and it competitively inhibits the binding of Wy-14643 (Pirinixic acid) (HY-16995) to the ligand binding domain of PPARα, suggesting that it functions as a PPARα ligand[2].
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