NBQX (disodium)
CAS No. : 479347-86-9
(Synonyms: FG9202 (disodium))
| Size | Price | Stock |
|---|---|---|
| 5mg | $99 | In-stock |
| 10mg | $150 | In-stock |
| 25mg | $300 | In-stock |
| 50mg | $450 | In-stock |
| 100mg | $675 | In-stock |
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| 500 mg | Get quote | |
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| Cat. No. : | HY-15068A |
| M.Wt: | 380.24 |
| Formula: | C12H6N4Na2O6S |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
NBQX disodium (FG9202 disodium) is a highly selective and competitive AMPA receptor antagonist. NBQX disodium has neuroprotective and anticonvulsant activity[1].
IC50 & Target: AMPA receptor[1]
In Vitro: NBQX disodium (FG9202 disodium) has a high affinity for AMPA and kainate binding sites with little or no affinity for the glutamate recognition site on the NMDA receptor complex[1].
In Vivo: NBQX disodium (FG9202; 20 mg/kg, i.p.; for 3 days) decreases seizures induced by PTZ[2].
NBQX disodium is neuroprotective in a focal ischaemia model in the rat when given as an i.v. bolus dose of 30 mg/kg at the time of MCA occlusion and again at 1 h post occlusion[1].
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