TC OT 39
CAS No. : 479232-57-0
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|---|---|---|
| 5mg | $514 | Get quote |
| 10mg | $823 | Get quote |
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| 100 mg | Get quote | |
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| Cat. No. : | HY-108678 |
| M.Wt: | 600.78 |
| Formula: | C32H40N8O2S |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
TC OT 39 is a synthetic oxytocin analog, as well as a selective agonist of oxytocin receptor (OXTR, EC50=180 nM). TC OT 39 is also an Avprla vasopressin receptor antagonist with an Ki value of 330 nM. TC OT 39 exhibits sedative effects in mouse models[1].
In Vivo:TC OT 39 (50 mg/kg, 75 mg/kg; i.p.; 4 times during 8-9 days) significantly decreases the marble burying at dose of 50 mg/kg, and shows overt sedative-like effects at dose of 75 mg/kg in C57BL/6J mice[1].
Marble burying is based on the natural instinct of rodents to bury objects, commonly used in preclinical research to assess anxiety-like behavior in rodents[1].
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