OT antagonist 1
CAS No. : 479080-38-1
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| Cat. No. : | HY-103650 |
| M.Wt: | 390.44 |
| Formula: | C22H22N4O3 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
OT antagonist 1 (Compound 4) is a potent, selective Oxytocin antagonist with a Ki of 50 nM. IC50 & Target: Ki: 50 nM (Oxytocin)[1] In Vitro: Oxytocin (OT) is a nonapeptide hormone that acts on the OT receptor, a seven-transmembrane (7TM) (Gq-coupled) receptor. The OT receptor has no subtypes but is related to the vasopressin receptors V1A, V1B and V2. OT antagonists have therapeutic potential in a number of areas including pre-term labour: Benign Prostatic Hyperplasia and sexual dysfunction. As a result there is significant interest in the identification of potent, selective, orally bioavailable OT antagonists[1].
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