Propyphenazone


CAS No. : 479-92-5

(Synonyms: 4-Isopropylantipyrine; Isopropylphenazone)

479-92-5
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Cat. No. : HY-A0273
M.Wt: 230.31
Formula: C14H18N2O
Purity: >98 %
Solubility: DMSO : ≥ 2.6 mg/mL
Introduction of 479-92-5 :

Propyphenazone (4-Isopropylantipyrine) is an orally active nonacidic pyrazole nonsteroidal anti-inflammatory drug (NSAID). Propyphenazone is a weak nonselective COX inhibitor. Propyphenazone has the effect of reducing pain and antipyretic activity with minimal anti-inflammatory activity[1][2]. In Vivo:Propyphenazone (4-Isopropylantipyrine; 0.7, 7, 70 mg/kg; oral gavage; the entire second week of gestation, days 8-14 of gestation), administered Propyphenazone:Caffeine and Propyphenazone:Paracetamol mixtures with constant 3:1 and 3:5 ratios, causes intrauterine growth retardation but does not increase external or internal congenital anomalies in pregnant Wistar rats[1].

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