2-Bromo-LSD


CAS No. : 478-84-2

(Synonyms: BOL-148; Bromolysergide)

478-84-2
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Cat. No. : HY-121675
M.Wt: 402.33
Formula: C20H24BrN3O
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 478-84-2 :

2-Bromo-LSD (BOL-148; Bromolysergide) is a Dopamine Receptor antagonist that directly affects dopamine neurons in the substantia nigra neostriatum. 2-Bromo-LSD increases the hydroxylation of tyrosine in striatum and antagonizes the decrease of Apomorphine-induced DOPA accumulation. 2-Bromo-LSD also blocks the 5-HT Receptor mediated DOPA formation[1]. In Vivo:2-Bromo-LSD (0.125-5.5mg/kg; i.p.; single dose) increases the in vivo tyrosine hydroxylation in the striatum of Male Sprague-Dawley rats, and increase the accumulation of DOPA with minimum effect dose of 0.125 mg/kg[1].

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