Buloxibutid


CAS No. : 477775-14-7

(Synonyms: AT2 receptor agonist C21)

477775-14-7
Price and Availability of CAS No. : 477775-14-7
Size Price Stock
5mg $120 In-stock
10mg $190 In-stock
25mg $350 In-stock
50mg $550 In-stock
100mg $950 In-stock
200 mg Get quote
500 mg Get quote
We match the lowest price on market.

We offer a substantial discount on larger orders, please inquire via [email protected]

or Fax: (86)21-58955996

Inquiry for price and availability only. Please place your order via our email or fax.

Cat. No. : HY-100113
M.Wt: 475.62
Formula: C23H29N3O4S2
Purity: >98 %
Solubility: DMSO : 100 mg/mL (210.25 mM; Need ultrasonic)
Introduction of 477775-14-7 :

AT2 receptor agonist C21 is a druglike selective angiotensin II AT2 receptor agonist with Ki values of 0.4 nM and >10 µM for the AT2 receptor and AT1 receptor, respectively[1]. IC50 & Target:Ki: 0.4 nM (AT2) and >10 µM (AT1)[1] In Vivo: AT2 receptor agonist C21, with a bioavailability of 20-30% after oral administration and a half-life estimated to 4 h in rat, induces outgrowth of neurite cells, stimulates p42/p44mapk, enhances in vivo duodenal alkaline secretion in Sprague-Dawley rats, and lowers the mean arterial blood pressure in anesthetized, spontaneously hypertensive rats[1].

Your information is safe with us.