Quipazine
CAS No. : 4774-24-7
| Size | Price | Stock |
|---|---|---|
| 250mg | $44 | In-stock |
| 500mg | $78 | In-stock |
| 1g | $114 | In-stock |
| 5g | $405 | In-stock |
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| Cat. No. : | HY-W028142 |
| M.Wt: | 213.28 |
| Formula: | C13H15N3 |
| Purity: | >98 % |
| Solubility: | DMSO : 8.33 mg/mL (ultrasonic;warming;heat to 60°C) |
Quipazine is a 5-HT agonist with a Ki value of 1.4 nM for displaces [3H]GR65630 from 5-HT3R in rat. Quipazine shows antiviral activity against SARS-CoV-2 with an EC50 of 31.64 μM. Quipazine behaves as a 5-HT3R agonist in peripheral models. Quipazine can be used for neurological disease research[1][2][3][4]. In Vitro:Quipazine shows binding efficacy to 5-HT1 and 5-HT2 with Ki values of 230 nM[3]. Quipazine displaces [3H]GR65630 from 5-HT3R in rat entorhinal cortex with a Ki value of 1.4 nM[3]. Quipazine shows antagonistic properties on the rat vagus nerve with pIC50 value of 6.1, 6.49 and 6.17 for 5-HT2, 5-HT1 and inhibition of 5-HT release[4]. In Vivo:Quipazine (2.5, 5 and 7.5 mg/kg, one dose for once; i.p.) affects dietary self-selection of different macronutrient diets in male and female rats[1].
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